Telomerases. Chemistry, Biology and Clinical Applications

Lue Neal

Жанр: Образовательная литература

Издательство: John Wiley & Sons Limited
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О книге "Telomerases. Chemistry, Biology and Clinical Applications"

This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research.

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Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed.

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